eLife (Mar 2021)

Rare variants increase the risk of severe COVID-19

Frank L van de Veerdonk,
Mihai G Netea

Affiliations

Frank L van de Veerdonk: ORCiD; Department of Internal Medicine, Radboudumc Center for Infectious Diseases, Nijmegen, Netherlands
Mihai G Netea: Department of Internal Medicine, Radboudumc Center for Infectious Diseases, Nijmegen, Netherlands; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany

DOI: https://doi.org/10.7554/eLife.67860
Journal volume & issue: Vol. 10

Abstract

Evidence is mounting that rare loss-of-function variants in the TLR7 gene predispose men with no medical history to severe forms of COVID-19.

Published in eLife

ISSN: 2050-084X (Online)
Publisher: eLife Sciences Publications Ltd
Country of publisher: United Kingdom
LCC subjects: Medicine; Science: Biology (General)
Website: https://elifesciences.org

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