Haematologica (Feb 2007)

Prothrombotic coagulation abnormalities in patients with newly diagnosed multiple myeloma

  • Johannes J.A. Auwerda,
  • Pieter Sonneveld,
  • Monica P.M. de Maat,
  • Frank W.G. Leebeek

DOI
https://doi.org/10.3324/haematol.10454
Journal volume & issue
Vol. 92, no. 2

Abstract

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Prothrombotic coagulation abnormalities were analyzed in patients with untreated multiple myeloma. Increases in factor VIII, in von Willebrand factor and a decrease in protein S were observed and these changes were strongly associated with disease stage. No difference in baseline coagulation parameters was found between patients with and without subsequent venous thromboembolism.