Xin yixue (Apr 2024)

Comparison of characteristics of cervical cancer screening history between cervical adenocarcinoma and cervical squamous cell carcinoma

  • Ye Minjuan, Li Jing, Chen Zifei, He Junxian, Chen Lifa, Zhang Yu

DOI
https://doi.org/10.3969/j.issn.0253-9802.2024.04.013
Journal volume & issue
Vol. 55, no. 4
pp. 311 – 316

Abstract

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Objective To comparatively analyze the characteristics of cervical cancer screening history between patients with cervical adenocarcinoma and cervical squamous cell carcinoma， and to preliminarily evaluate the efficacy of cervical cancer screening for precancerous lesions of cervical adenocarcinoma. Methods Clinical data of 117 patients with cervical adenocarcinoma and 712 patients with cervical squamous cell carcinoma were retrospectively analyzed， and the differences in cervical cancer screening history were statistically analyzed between two groups. Results The proportion of cervical adenocarcinoma patients receiving cervical cancer screening was 24.5%， significantly higher than 6.8% of those with cervical squamous cell carcinoma （P < 0.001）. The proportion of cervical adenocarcinoma patients receiving regular screening or above was 18.4%， significantly higher than 2.8% of those with cervical squamous cell carcinoma （P < 0.001）. The proportion of symptom-detected cervical squamous cell carcinoma was 91.6%， significantly higher than 79.1% of their counterparts with cervical adenocarcinoma cell carcinoma （P < 0.001）. The proportion of screening-detected stageⅠ-ⅡA cervical adenocarcinoma was 24.6%， significantly higher than 11.1% of those with screening-detected stage Ⅰ-ⅡA cervical squamous cell carcinoma （P = 0.004）. The proportion of screening-detected stageⅠ-ⅡA cervical adenocarcinoma was 24.6%， significantly higher than 4.0% of those with screening-detected stageⅡB-Ⅳ cervical adenocarcinoma （P = 0.022）. Conclusions Current cervical cancer screening regimen yields higher efficacy for precancerous lesions of cervical squamous cell carcinoma compared with cervical adenocarcinoma. However， it still contributes to the diagnosis of early cervical adenocarcinoma. Therefore， extensive attention should be paid to cervical cancer screening. Cervical cancer screening regimen remains to be further optimized.

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