Nature Communications (Nov 2021)

Machine learning of genomic features in organotropic metastases stratifies progression risk of primary tumors

  • Biaobin Jiang,
  • Quanhua Mu,
  • Fufang Qiu,
  • Xuefeng Li,
  • Weiqi Xu,
  • Jun Yu,
  • Weilun Fu,
  • Yong Cao,
  • Jiguang Wang

DOI
https://doi.org/10.1038/s41467-021-27017-w
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 15

Abstract

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The location and timing of metastasis are still fundamentally unpredictable. Here the authors present the Metastatic Network model, a machine learning framework that integrates clinical data and DNA alterations to predict the risk of metastasis to specific organs as well as clinical outcomes