European Journal of Case Reports in Internal Medicine (Mar 2024)

Baker’s yeast might not always be good for everyone – a case of percutaneous gastrostomy tube induced Saccharomyces cerevisiae peritonitis in an immunocompromised patient

  • Mohammad Kloub,
  • Muhammad Hussain,
  • Fnu Marium,
  • Atheer Anwar,
  • Ahmad Haddad,
  • Jihad Slim,
  • Yatinder Bains

DOI
https://doi.org/10.12890/2024_004354

Abstract

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Peritonitis, the inflammation of the protective membrane surrounding parts of the abdominal organs, is a common clinical pathology with multifactorial aetiologies. While bacterial infections are well-recognised as a cause of peritonitis, fungal infections remain relatively uncommon especially Saccharomyces cerevisiae, which is commonly used for breadmaking and as a nutritional supplement. This fungus has been reported to induce peritonitis in patients on peritoneal dialysis. However, it has never been reported as secondary to percutaneous endoscopic gastrostomy (PEG) tube insertion in immunocompromised patients. We present a 64-year-old female with a history of human immunodeficiency virus (HIV) who developed S. cerevisiae peritonitis following PEG tube insertion. The case highlights the importance of considering rare organisms when treating immunocompromised patients with peritonitis, especially after gastrointestinal tract penetration or peritoneal membrane disruption.

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