High Sensitive CRP in Behcet Disease With and Without Uveitis Compared With Idiopathic Uveitis: A Cross-Sectional Study

Abstract

Background: Uveitis is one of the important manifestations of Behcet disease (BD). High sensitive C-reactive protein (hs-CRP) is an acute phase reactant, which may increase in BD. There are controversies in different studies regarding the relation between hs-CRP and uveitis in BD. This study aimed to determine serum values of hs-CRP and its relationship with uveitis in BD. Methods: A total of 94 patients, divided into 3 groups (Behcet"s uveitis (n = 31), Behcet"s without uveitis (n = 37) and idiopathic uveitis (n = 26), participated in the study. Serum levels of hs-CRP were compared among those groups. Result: The mean serum hs-CRP level was 6.49 ± 3.27 mg/L (BD with uveitis), 6.41 ± 3.85 mg/L (BD without uveitis) and 6.97±3.9 mg/L (idiopathic uveitis. Tukey test was done among groups and there were no significant differences between them (P = 0.69). Conclusion: Our results revealed no significant difference among the 3 groups regarding the mean serum hs-CRP level. However, further studies are warranted in this regard.

Keywords

• Behcet syndrome
• High sensitive C-reactive protein
• hs-CRP
• Uveitis
• Idiopathic uveitis