Revista de la Sociedad Argentina de Diabetes (Sep 2022)
Symposium 4: Assisted fertilization and maternal diabetes mellitus
Abstract
Type 1 and 2 diabetes mellitus (DM) are among the most prevalent chronic diseases in women of reproductive age. In turn, they are patients with alterations in their fertility where it is observed that they have fewer offspring than their peers and several must undergo highly complex fertility treatments. The hyperglycemia of DM1 (due to insulin deficiency) and hyperinsulinemia (due to exogenous administration) can induce hypogonadism, ovaries with a polycystic appearance and hyperandrogenism. In the case of DM2, patients may present with polycystic ovary syndrome (PCOS), obesity, insulin resistance and chronic inflammation, all of which explains the greater difficulty in achieving pregnancy.
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