Patient Preference and Adherence (Mar 2023)

Sleep Disturbance and Immunological Consequences of COVID-19

  • Bocek J,
  • Prasko J,
  • Genzor S,
  • Hodny F,
  • Vanek J,
  • Pobeha P,
  • Belohradova K,
  • Ociskova M

Journal volume & issue
Vol. Volume 17
pp. 667 – 677

Abstract

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Jonas Bocek,1 Jan Prasko,1– 4,* Samuel Genzor,5,* Frantisek Hodny,1,* Jakub Vanek,1,* Pavol Pobeha,6,* Kamila Belohradova,1,* Marie Ociskova1,4,* 1Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital, Olomouc, The Czech Republic; 2Department of Psychology Sciences, Faculty of Social Science and Health Care, Constantine the Philosopher University in Nitra, Nitra, The Slovak Republic; 3Department of Psychotherapy, Institute for Postgraduate Training in Health Care, Prague, The Czech Republic; 4Rehabilitation Hospital Beroun, Jessenia Inc, Akeso Holding, Beroun, The Czech Republic; 5Department of Respiratory Medicine, Faculty of Medicine and Dentistry, University Palacky Olomouc and University Hospital, Olomouc, The Czech Republic; 6Department of Respiratory Diseases and Tuberculosis University Hospital and Faculty of Medicine and Dentistry Pavol Jozef Safarik University, Kosice, The Slovak Republic*These authors contributed equally to this workCorrespondence: Jan Prasko, Department of Psychiatry, Faculty of Medicine and Dentistry, Palacky University Olomouc, University Hospital, I. P. Pavlova 6, Olomouc, 77520, The Czech Republic, Tel +420 603 414 930, Email [email protected]: The overarching importance of sleep was further emphasized during the pandemic of COVID-19. The subjects infected by COVID-19 frequently experience sleep disturbances; some are long-lasting problems and decrease the quality of life. Insomnia is the most studied sleep disorder associated with COVID-19. Insomnia affects patients who have experienced an infection and the general population. Good sleep is important in maintaining mental and physical health, including immune system functions. The interconnections between insomnia, the immune system, and COVID-19 are complex. Insomnia triggers numerous immune system dysregulations and makes individuals more vulnerable to respiratory infections. This narrative review overviews the influence of the COVID-19 pandemic on the immune system through sleep disorders.Keywords: insomnia, COVID-19, circadian rhythms, immunity, sleep deprivation, mental disorders

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