Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium

Fulvia Ceccarelli; Marcello Govoni; Matteo Piga; Giulia Cassone; Francesco Paolo Cantatore; Giulio Olivieri; Alberto Cauli; Ennio Giulio Favalli; Fabiola Atzeni; Elisa Gremese; Florenzo Iannone; Roberto Caporali; Marco Sebastiani; Gian Franco Ferraccioli; Giovanni Lapadula; Fabrizio Conti

doi:10.3390/jcm11206016

Journal of Clinical Medicine (Oct 2022)

Arthritis in Systemic Lupus Erythematosus: From 2022 International GISEA/OEG Symposium

Fulvia Ceccarelli,
Marcello Govoni,
Matteo Piga,
Giulia Cassone,
Francesco Paolo Cantatore,
Giulio Olivieri,
Alberto Cauli,
Ennio Giulio Favalli,
Fabiola Atzeni,
Elisa Gremese,
Florenzo Iannone,
Roberto Caporali,
Marco Sebastiani,
Gian Franco Ferraccioli,
Giovanni Lapadula,
Fabrizio Conti

Affiliations

Fulvia Ceccarelli: Lupus Clinic, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University of Rome, 00161 Rome, Italy
Marcello Govoni: Rheumatology Unit, Department of Medical Sciences, Azienda Ospedaliero-Universitaria S. Anna–Ferrara, University of Ferrara, 44124 Ferrara, Italy
Matteo Piga: Rheumatology Unit, Department of Medical Sciences and Public Health, University Clinic and AOU of Cagliari, 09042 Cagliari, Italy
Giulia Cassone: Rheumatology Unit, Department of Surgery, Medicine, Dentistry and Morphological Sciences with Transplant Surgery, Oncology and Regenerative Medicine Relevance, University of Modena and Reggio Emilia, 41121 Modena, Italy
Francesco Paolo Cantatore: Rheumatology Clinic, UOC Reumatologia Universitaria, “Ospedali Riuniti” di Foggia, 71122 Foggia, Italy
Giulio Olivieri: Lupus Clinic, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University of Rome, 00161 Rome, Italy
Alberto Cauli: Rheumatology Unit, Department of Medical Sciences and Public Health, University Clinic and AOU of Cagliari, 09042 Cagliari, Italy
Ennio Giulio Favalli: Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, 20122 Milan, Italy
Fabiola Atzeni: Rheumatology Unit, Department of Experimental and Internal Medicine, University of Messina, 98122 Messina, Italy
Elisa Gremese: Rheumatology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy
Florenzo Iannone: Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, 70121 Bari, Italy
Roberto Caporali: Division of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, 20122 Milan, Italy
Marco Sebastiani: Rheumatology Unit, Department of Surgery, Medicine, Dentistry and Morphological Sciences with Transplant Surgery, Oncology and Regenerative Medicine Relevance, University of Modena and Reggio Emilia, 41121 Modena, Italy
Gian Franco Ferraccioli: School of Medicine, Università Cattolica del Sacro Cuore, 00168 Rome, Italy
Giovanni Lapadula: Rheumatology Unit, Department of Emergency Surgery and Organ Transplantations, University of Bari, 70121 Bari, Italy
Fabrizio Conti: Lupus Clinic, Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza University of Rome, 00161 Rome, Italy

DOI: https://doi.org/10.3390/jcm11206016
Journal volume & issue: Vol. 11, no. 20
p. 6016

Abstract

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Musculoskeletal involvement is one of the most common manifestations of systemic lupus erythematosus (SLE), with a negative impact on both quality of life and overall prognosis. SLE arthritis can be classified into three different subtypes, with different prevalence and characteristic biomarkers and MRI findings. Identifying the pathogenetic mechanisms underlying musculoskeletal manifestations’ development is crucial to develop therapeutic strategies to suppress synovial inflammation, prevent erosions and deformities, and improve SLE patients’ quality of life. Hence, here we discuss the main pathogenetic mechanisms and therapeutic approaches of musculoskeletal manifestations of SLE from the 2022 International GISEA/OEG Symposium.

Published in Journal of Clinical Medicine

ISSN: 2077-0383 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/jcm

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