Communications Biology (Oct 2022)

Noradrenergic consolidation of social recognition memory is mediated by β-arrestin–biased signaling in the mouse prefrontal cortex

  • Deqin Cheng,
  • Junwen Wu,
  • Enhui Yan,
  • Xiaocen Fan,
  • Feifei Wang,
  • Lan Ma,
  • Xing Liu

DOI
https://doi.org/10.1038/s42003-022-04051-y
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 13

Abstract

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Social memory consolidation requires norepinephrine release in the medial prefrontal cortex (mPFC), and enhancing beta-arrestin signaling in the mPFC restores social recognition memory that is normally impaired by age in mice.