Nature Communications (Feb 2023)

Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions

  • Nai-Chi Chen,
  • Chun-Hsiung Wang,
  • Masato Yoshimura,
  • Yi-Qi Yeh,
  • Hong-Hsiang Guan,
  • Phimonphan Chuankhayan,
  • Chien-Chih Lin,
  • Pei-Ju Lin,
  • Yen-Chieh Huang,
  • Soichi Wakatsuki,
  • Meng-Chiao Ho,
  • Chun-Jung Chen

DOI
https://doi.org/10.1038/s41467-023-36235-3
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 15

Abstract

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Viruses can cause Colony Collapse Disorder, leading to large losses of honeybee hives globally. In this study, the authors solve capsid structures of honeybee-infecting Lake Sinai viruses and identify distinct features, which advances understanding of viral dynamics, assembly and infection mechanisms.