Nature Communications (May 2021)

Yeast cell fate control by temporal redundancy modulation of transcription factor paralogs

  • Yan Wu,
  • Jiaqi Wu,
  • Minghua Deng,
  • Yihan Lin

DOI
https://doi.org/10.1038/s41467-021-23425-0
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 13

Abstract

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How dynamic transcription factors temporally interact to regulate stress survival in yeast is currently unclear. Here the authors integrate single-cell imaging, RNA-seq, and modeling to identify a new cell fate control mechanism mediated by temporal redundancy modulation during yeast stress response.