Communications Biology (Jan 2022)
Haploidy in somatic cells is induced by mature oocytes in mice
- Yeonmi Lee,
- Aysha Trout,
- Nuria Marti-Gutierrez,
- Seoon Kang,
- Philip Xie,
- Aleksei Mikhalchenko,
- Bitnara Kim,
- Jiwan Choi,
- Seongjun So,
- Jongsuk Han,
- Jing Xu,
- Amy Koski,
- Hong Ma,
- Junchul David Yoon,
- Crystal Van Dyken,
- Hayley Darby,
- Dan Liang,
- Ying Li,
- Rebecca Tippner-Hedges,
- Fuhua Xu,
- Paula Amato,
- Gianpiero D. Palermo,
- Shoukhrat Mitalipov,
- Eunju Kang
Affiliations
- Yeonmi Lee
- Department of Biomedical Science, College of Life Science, CHA University
- Aysha Trout
- The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine
- Nuria Marti-Gutierrez
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Seoon Kang
- Department of Biomedical Science, College of Life Science, CHA University
- Philip Xie
- The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine
- Aleksei Mikhalchenko
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Bitnara Kim
- Department of Biomedical Science, College of Life Science, CHA University
- Jiwan Choi
- Department of Biomedical Science, College of Life Science, CHA University
- Seongjun So
- Department of Biomedical Science, College of Life Science, CHA University
- Jongsuk Han
- Department of Biomedical Science, College of Life Science, CHA University
- Jing Xu
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Amy Koski
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Hong Ma
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Junchul David Yoon
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Crystal Van Dyken
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Hayley Darby
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Dan Liang
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Ying Li
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Rebecca Tippner-Hedges
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Fuhua Xu
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Paula Amato
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Gianpiero D. Palermo
- The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine
- Shoukhrat Mitalipov
- Center for Embryonic Cell and Gene Therapy, Oregon Health and Science University
- Eunju Kang
- Department of Biomedical Science, College of Life Science, CHA University
- DOI
- https://doi.org/10.1038/s42003-022-03040-5
- Journal volume & issue
-
Vol. 5,
no. 1
pp. 1 – 15
Abstract
Yeonmi Lee, Aysha Trout, Nuria Marti-Guiterrez et al. examine different aspects of somatic cell haploidization in mouse enucleated oocytes. Their results provide further insight into generating oocytes carrying somatic genomes.
