Research and Application of Metal–Organic Framework in Surface Modification of Biomaterials—A Review

Abstract

Surface modification is one of the core technologies in the field of biomedical materials. The fundamental purpose is to enable the surface of biomass materials to have better biocompatibility to better meet clinical needs. A metal–organic framework (MOF) is composed of organic links and metal nodes. It is a type of new crystal porous material with important application potential. In recent years, it has been explored in the field of biomass materials. This review introduces the structure and synthesis of MOF and systematically combs, summarizes and evaluates the research and application of MOF in cardiovascular therapy, tumor therapy, bone tissue engineering and other scenarios, in order to provide reference and inspiration for subsequent researchers.

Keywords

• metal–organic frameworks
• surface modification
• antibacterial performance
• cardiovascular treatment
• drug transmission