Mucormycotic osteomyelitis involving maxilla in SARS-CoV-2 prediabetic patient: A case report

Abstract

SARS-CoV-2, a respiratory corona virus, zoonotic disease and a global pandemic burden demonstrates a myriad of clinical and oral manifestations that have been documented in yester years. The clinical manifestations include sore throat, fever, dyspnea and anosmia (partial or complete loss of smell). The oral manifestations include xerostomia, candidiasis, and hyperpigmentation of melanin, oral ulcerations and ageusia (loss of taste sensation). These findings were further worsened in patients with co-morbidities such as diabetes, cardiovascular diseases, immunosuppression, pro-inflammatory or pro-coagulative states. The possibility of fungal infections with invasive mycosis has also been documented. However, the occurrence of this deadly virus in pre-diabetic case is a rarity that needs to be explored so as to affirm the hypothesis that hyperglycemia was due to viral induced phenomena or thereof. We report here, one such rare case of mucormycotic osteomyelitis of maxilla manifested after few months in SARS-CoV-2 positive patient with no previous history of diabetes but marked increase in blood sugar level, when infected with corona virus, which can be tagged as a case of non-diabetic hyperglycemia/pre-diabetes/impaired glucose regulation (raised blood glucose level but not in the diabetic range).

Keywords

• mucormycosis
• sars-cov-2
• osteomyelitis
• non-diabetic hyperglycemia
• pre-diabetes
• mobile maxillary teeth