Nature Communications (Apr 2023)
Pulmonary inflammation promoted by type-2 dendritic cells is a feature of human and murine schistosomiasis
- E. L. Houlder,
- A. H. Costain,
- I. Nambuya,
- S. L. Brown,
- J. P. R. Koopman,
- M. C. C. Langenberg,
- J. J. Janse,
- M. A. Hoogerwerf,
- A. J. L. Ridley,
- J. E. Forde-Thomas,
- S. A. P. Colombo,
- B. M. F. Winkel,
- A. A. Galdon,
- K. F. Hoffmann,
- P. C. Cook,
- M. Roestenberg,
- H. Mpairwe,
- A. S. MacDonald
Affiliations
- E. L. Houlder
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- A. H. Costain
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- I. Nambuya
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- S. L. Brown
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- J. P. R. Koopman
- Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Centre
- M. C. C. Langenberg
- Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Centre
- J. J. Janse
- Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Centre
- M. A. Hoogerwerf
- Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Centre
- A. J. L. Ridley
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- J. E. Forde-Thomas
- Department of Life Sciences, Aberystwyth University
- S. A. P. Colombo
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- B. M. F. Winkel
- Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Centre
- A. A. Galdon
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- K. F. Hoffmann
- Department of Life Sciences, Aberystwyth University
- P. C. Cook
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- M. Roestenberg
- Leiden University Center for Infectious Diseases (LU-CID), Leiden University Medical Centre
- H. Mpairwe
- MRC/UVRI and LSHTM Uganda Research Unit
- A. S. MacDonald
- Lydia Becker Institute of Immunology and Inflammation, University of Manchester
- DOI
- https://doi.org/10.1038/s41467-023-37502-z
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 12
Abstract
Schistosomiasis, a parasitic helminth infection, causes pulmonary symptoms during acute and chronic infection. Here, Houlder et al characterise the pulmonary immune response and demonstrate the role type 2 dendritic cells play in lung inflammation.
