Covalent Organic Frameworks (COFs) as Multi-Target Multifunctional Frameworks
Syed Nasir Abbas Bukhari,
Naveed Ahmed,
Muhammad Wahab Amjad,
Muhammad Ajaz Hussain,
Mervat A. Elsherif,
Hasan Ejaz,
Nasser H. Alotaibi
Affiliations
Syed Nasir Abbas Bukhari
Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia
Naveed Ahmed
Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia
Muhammad Wahab Amjad
Center for Ultrasound Molecular Imaging and Therapeutics, Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA 15213, USA
Muhammad Ajaz Hussain
Centre for Organic Chemistry, School of Chemistry, University of the Punjab, Lahore 54590, Pakistan
Mervat A. Elsherif
Chemistry Department, College of Science, Jouf University, Sakaka 72388, Saudi Arabia
Hasan Ejaz
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia
Nasser H. Alotaibi
Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia
Covalent organic frameworks (COFs), synthesized from organic monomers, are porous crystalline polymers. Monomers get attached through strong covalent bonds to form 2D and 3D structures. The adjustable pore size, high stability (chemical and thermal), and metal-free nature of COFs make their applications wider. This review article briefly elaborates the synthesis, types, and applications (catalysis, environmental Remediation, sensors) of COFs. Furthermore, the applications of COFs as biomaterials are comprehensively discussed. There are several reported COFs having good results in anti-cancer and anti-bacterial treatments. At the end, some newly reported COFs having anti-viral and wound healing properties are also discussed.