Nature Communications (Oct 2022)

Aversive memory formation in humans involves an amygdala-hippocampus phase code

  • Manuela Costa,
  • Diego Lozano-Soldevilla,
  • Antonio Gil-Nagel,
  • Rafael Toledano,
  • Carina R. Oehrn,
  • Lukas Kunz,
  • Mar Yebra,
  • Costantino Mendez-Bertolo,
  • Lennart Stieglitz,
  • Johannes Sarnthein,
  • Nikolai Axmacher,
  • Stephan Moratti,
  • Bryan A. Strange

DOI
https://doi.org/10.1038/s41467-022-33828-2
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 16

Abstract

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The amygdala facilitates memory encoding in the hippocampus. Here the authors show, using simultaneous intracranial recordings from these regions, that emotional memory encoding is mediated by the amygdala theta phase to which hippocampal gamma activity and neuronal firing is coupled.