Nature Communications (Oct 2021)

Efficient and precise single-cell reference atlas mapping with Symphony

  • Joyce B. Kang,
  • Aparna Nathan,
  • Kathryn Weinand,
  • Fan Zhang,
  • Nghia Millard,
  • Laurie Rumker,
  • D. Branch Moody,
  • Ilya Korsunsky,
  • Soumya Raychaudhuri

DOI
https://doi.org/10.1038/s41467-021-25957-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 21

Abstract

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The number of single-cell RNA-seq datasets generated is increasing rapidly, making methods that map cell types to well-curated references increasingly important. Here, the authors propose an accurate method for mapping single cells onto a reference atlas in seconds.