E3S Web of Conferences (Jan 2024)

Combined effects of deltamethrin and T-2 toxin on animals during the use of bentonite

  • Egorov Vladislav,
  • Valiullin Lenar,
  • Raginov Ivan,
  • Alekseyko Leonid,
  • Klimovich Sergey,
  • Pamirsky Igor,
  • Zakharenko Alexander,
  • Yampolsky İlya,
  • Golokhvast Kirill

DOI
https://doi.org/10.1051/e3sconf/202454801017
Journal volume & issue
Vol. 548
p. 01017

Abstract

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This study investigated the combined effects of deltamethrin and T-2 toxin on animals, utilizing bentonite as a prophylactic agent. The research was conducted on white rats, which were orally administered the toxins for 20 consecutive days. Subsequently, clinical, hematological, and biochemical parameters were examined to assess the impact of the toxins on the animals. Based on research results, it has been established that the combined effect of deltamethrin and T-2 toxin with repeated administration is characterized by more severe clinical, hematological and biochemical changes than with separate exposure to toxicants. Accompanied by a decrease in the number of leukocytes, erythrocytes and hemoglobin, a decrease in total protein, glucose and cholinesterase activity. Adding bentonite to the feed as a prophylactic agent at a dose of 2% of the diet has a preventive effect in case of combined poisoning with deltamethrin and T- 2 toxin, and helps to normalize the clinical, hematological and biochemical parameters of animals.