Children
(Dec 2017)
A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review
Pablo Manresa,
Fabián Tarín,
María Niveiro,
María Tasso,
Olga Alda,
Francisco López,
Héctor Sarmiento,
José J. Verdú,
Francisco De Paz,
Silvia López,
María Del Cañizo,
Esperanza Such,
Eva Barragán,
Fernanda Martirena
Affiliations
Pablo Manresa
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
Fabián Tarín
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
María Niveiro
Department of Anatomic Pathology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
María Tasso
Department of Pediatrics, Hospital General Universitario de Alicante, 03010 Alicante, Spain
Olga Alda
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
Francisco López
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
Héctor Sarmiento
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
José J. Verdú
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
Francisco De Paz
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
Silvia López
Department of Pediatrics, Hospital General Universitario de Alicante, 03010 Alicante, Spain
María Del Cañizo
Department of Pediatrics, Hospital General Universitario de Alicante, 03010 Alicante, Spain
Esperanza Such
Department of Hematology, Hospital Universitario La Fe de Valencia, 46009 Valencia, Spain
Eva Barragán
Department of Hematology, Hospital Universitario La Fe de Valencia, 46009 Valencia, Spain
Fernanda Martirena
Department of Hematology, Hospital de Elda, 03600 Elda, Alicante, Spain
DOI
https://doi.org/10.3390/children4120113
Journal volume & issue
Vol. 4,
no. 12
p.
113
Abstract
Read online
We describe an exceptional case of erythroid sarcoma in a pediatric patient as a growing orbital mass with no evidence of morphologic bone marrow involvement, who was finally diagnosed of pure erythroid sarcoma based on histopathology and flow cytometry criteria. We discuss the contribution of standardized eight-color flow cytometry as a rapid and reliable diagnostic method. The use of normal bone marrow databases allowed us to identify small aberrant populations in bone marrow and later confirm the diagnosis in the neoplastic tissue.
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