Bulletin of the Chemical Society of Ethiopia (Jun 2005)

<b>Diospyrone, a new coumarinylbinaphthoquinone from <i>Diospyros canaliculata</i> (Ebenaceae): structure and antimicrobial activity</b>

  • J.G. Tangmouo,
  • D. Lontsi,
  • F.N. Ngounou,
  • V. Kuete,
  • A.L. Meli,
  • R.N. Manfouo,
  • H.W. Kamdem,
  • P. Tane,
  • V. Penlap Beng,
  • B.L.Sondengam,
  • J.D. Connolly

Journal volume & issue
Vol. 19, no. 1
pp. 81 – 88

Abstract

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A new binaphthoquinone bearing two 4-hydroxy-5-methylcoumarin-3-yl units has been isolated from the stem bark of Diospyros canaliculata De Wildeman in addition to five known compounds: lupenone, betulinic acid, gerberinol, plumbagin and canaliculatin. Their structures were established on the basis of 1D (1H, 13C and DEPT) and 2D (1H-1H COSY, HMQC and HMBC) NMR experiments. Some of the above compounds showed a significant antimicrobial activity against bacteria and yeasts.

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