Romanian Journal of Laboratory Medicine (Dec 2015)

Uric Acid, Oxidative Stress and Inflammation in Chronic Heart Failure with Reduced Ejection Fraction

  • Iliesiu Adriana,
  • Campeanu Alexandru,
  • Marta Daciana,
  • Parvu Irina,
  • Gheorghe Gabriela

DOI
https://doi.org/10.1515/rrlm-2015-0039
Journal volume & issue
Vol. 23, no. 4
pp. 397 – 406

Abstract

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Background. Oxidative stress (OS) and inflammation are major mechanisms involved in the progression of chronic heart failure (CHF). Serum uric acid (sUA) is related to CHF severity and could represent a marker of xanthine-oxidase activation. The relationship between sUA, oxidative stress (OS) and inflammation markers was assessed in patients with moderate-severe CHF and reduced left ventricular (LV) ejection fraction (EF).

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