Case Reports in Dermatology (Jan 2021)

Mycosis Fungoides with Dermal Mucin Deposition: An Unusual Variant of the Most Challenging Primary Cutaneous Lymphoma

  • Alessandra Filosa,
  • Stefano Simonetti,
  • Magda Zanelli,
  • Maurizio Zizzo,
  • Luca Stingeni,
  • Giovanni Martino,
  • Guido Collina,
  • Stefano Ascani

DOI
https://doi.org/10.1159/000509525
Journal volume & issue
Vol. 13, no. 1
pp. 7 – 11

Abstract

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Mycosis fungoides (MF) is defined as an epidermotropic primary cutaneous T-cell lymphoma composed of small-to-medium-sized T lymphocytes with cerebriform nuclei and with a T-helper phenotype. LeBoit first described an unusual variant of MF with dermal acid mucin deposition. Such a variant was still considered in the list of clinicopathological variants of MF by Cerroni and colleagues. We herein report a case of patch-stage MF with abundant papillary dermal mucin deposition in a clinical setting of an erythematous patch on the lower abdomen and thigh.

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