Tryptophan End-Tagging Confers Antifungal Activity on a Tick-Derived Peptide by Triggering Reactive Oxygen Species Production

• Court K. Chiramba,
• Dalton S. Möller,
• Christian D. Lorenz,
• Rumbidzai R. Chirombo,
• A. James Mason,
• Megan J. Bester,
• Anabella R. M. Gaspar

Affiliations

Court K. Chiramba

Department of Biochemistry, Genetics and Microbiology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa

Dalton S. Möller

Department of Biochemistry, Genetics and Microbiology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa

Christian D. Lorenz

Department of Physics, King’s College London, London, U.K.

Rumbidzai R. Chirombo

Department of Anatomy, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa

A. James Mason

Institute of Pharmaceutical Science, School of Cancer & Pharmaceutical Science, King’s College London, London, U.K.

Megan J. Bester

Department of Anatomy, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa

Anabella R. M. Gaspar

Department of Biochemistry, Genetics and Microbiology, Faculty of Natural and Agricultural Sciences, University of Pretoria, Pretoria, South Africa