Nature Communications (Nov 2019)

Infant airway microbiota and topical immune perturbations in the origins of childhood asthma

  • Jonathan Thorsen,
  • Morten A. Rasmussen,
  • Johannes Waage,
  • Martin Mortensen,
  • Asker Brejnrod,
  • Klaus Bønnelykke,
  • Bo L. Chawes,
  • Susanne Brix,
  • Søren J. Sørensen,
  • Jakob Stokholm,
  • Hans Bisgaard

DOI
https://doi.org/10.1038/s41467-019-12989-7
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 8

Abstract

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Here, Thorsen et al. examine the microbiota during the first three months of life in a cohort of 700 children and find that microbial diversity and the relative abundances of Veillonella and Prevotella in the airways at one month of age are associated with topical immune mediators and asthma by age 6 years.