Optimising the management of childhood acute diarrhoeal disease using a rapid test-and- treat strategy and/or Lactobacillus reuteri DSM 17938: a multicentre, randomised, controlled, factorial trial in Botswana

• Lehana Thabane,
• Andrew P Steenhoff,
• Charles Muthoga,
• Marek Smieja,
• Ketil Størdal,
• Loeto Mazhani,
• Jeffrey M Pernica,
• Thuvaraha Vanniyasingam,
• Margaret Mokomane,
• David M Goldfarb,
• Tonya Arscott-Mills,
• Banno Moorad,
• Mbabi Bapabi,
• Kwana Lechiile,
• Oarabile Mangwegape,
• Boswa Batisani,
• Norah Mawoko,
• Joycelyne Ewusie,
• Amy Lowe,
• Janice M Bonsu,
• Alemayehu M Gezmu,
• Matthew S Kelly

Affiliations

Lehana Thabane

Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada

Andrew P Steenhoff

12 Infectious Diseases, Global Health Center, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

Charles Muthoga

Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana

Marek Smieja

Department of Pathology and Molecular Medicine, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

Ketil Størdal

1 Department of Paediatrics and Adolescence Medicine, Østfold Hospital Trust, Grålum, Norway

Loeto Mazhani

10 Pediatrics, University of Botswana Faculty of Health Sciences, Gaborone, Gaborone, Botswana

Jeffrey M Pernica

Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada

Thuvaraha Vanniyasingam

St Joseph`s Healthcare Hamilton, Hamilton, Ontario, Canada

Margaret Mokomane

5National Tuberculosis Reference Laboratory, Ministry of Health and Wellness, Gaborone, Botswana

David M Goldfarb

Healthy Starts, British Columbia Children’s Hospital Research Institute, Vancouver, British Columbia, Canada

Tonya Arscott-Mills

Botswana-UPenn Partnership, Gaborone, Botswana

Banno Moorad

Botswana-UPenn Partnership, Gaborone, Botswana

Mbabi Bapabi

Botswana-UPenn Partnership, Gaborone, Botswana

Kwana Lechiile

Botswana-UPenn Partnership, Gaborone, Botswana

Oarabile Mangwegape

Botswana-UPenn Partnership, Gaborone, Botswana

Boswa Batisani

Botswana-UPenn Partnership, Gaborone, Botswana

Norah Mawoko

Botswana-UPenn Partnership, Gaborone, Botswana

Joycelyne Ewusie

Department of Health Research Methods, Evidence, and Impact, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada

Amy Lowe

Department of Global Health, McMaster University, Hamilton, Ontario, Canada

Janice M Bonsu

University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA

Alemayehu M Gezmu

Department of Pediatrics and Adolescent Health, University of Botswana, Gaborone, Botswana

Matthew S Kelly

Department of Pediatrics, Duke University, Durham, North Carolina, USA