Molbank (Apr 2015)

3-Chlorokenpaullone

  • Oliver C. F. Orban,
  • Ricarda S. Korn,
  • Lisa Unger,
  • Akim Yildiz,
  • Conrad Kunick

DOI
https://doi.org/10.3390/M856
Journal volume & issue
Vol. 2015, no. 2
p. M856

Abstract

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3-Chlorokenpaullone (9-bromo-3-chloro-7,12-dihydroindolo[3,2-d][1]benz­azepin-6(5H)-one) is a novel derivative of the protein kinase inhibitor kenpaullone. The title compound was synthesized by a Fischer indole reaction from 8-chloro-3,4-dihydro-1H-1-benzazepin-2,5-dione and 4-bromophenylhydrazine. It was characterized for structural identity by elemental analysis and spectroscopic methods (IR, NMR, EI-MS) and checked for purity by HPLC.

Keywords