The relationship between renal functions and thrombolysis in myocardial infarction frame count in patients with slow coronary flow

Abstract

We investigated the relationship between renal function and coronary thrombolysis in myocardial infarction frame count (TFC) in patients with slow coronary flow (SCF). The patient group was composed of 34 patients with SCF. The control group was made up of 34 well-matched individuals who have normal SCF in their coronary arteries. The coronary flow rates of all subjects were documented by TFC. Glomerular filtration rate (GFR) and corrected GFR (cGFR) were calculated by creatinine clearance according to the Cockcroft-Gault formula. There is no difference in the gender or age of the groups. Blood urea nitrogen and creatinine were significantly higher in the SCF group compared the control group (blood urea nitrogen: 17±6 mg/dL vs. 14±4 mg/dL, p=0.04 and creatine: 0.9±0.1 mg/dL vs. 0.7±0.1 mg/dL, p=0.01). GFR and cGFR were significantly different between the groups (GFR: 92±28 mL/min vs. 112±27 mL/min, p=0.004 and cGFR: 77±22 mL/min/1.73 m2 vs. 96±24 mL/min/1.73 m2, p=0.007). There was a negative correlation between GFR/cGFR and TFC in all coronary arteries. This study shows that impaired renal function is associated with SCF. Patients with SCF have worse renal function compared with patients without SCF.

Keywords

• Endothelial dysfunction
• Renal functions
• Slow coronary flow