mBio
(Apr 2021)
Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication
Lily E. Adams,
Kenneth H. Dinnon,
Yixuan J. Hou,
Timothy P. Sheahan,
Mark T. Heise,
Ralph S. Baric
Affiliations
Lily E. Adams
ORCiD Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Kenneth H. Dinnon
Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Yixuan J. Hou
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Timothy P. Sheahan
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Mark T. Heise
ORCiD Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Ralph S. Baric
ORCiD Department of Microbiology & Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
DOI
https://doi.org/10.1128/mBio.03149-20
Journal volume & issue
Vol. 12,
no. 2
Abstract
Read online
SARS-CoV-2 (the causative agent of COVID-19) is a major public health threat and one of two related coronaviruses that have caused epidemics in modern history. A method of screening potential infectible hosts for preemergent and future emergent coronaviruses would aid in mounting rapid response and intervention strategies during future emergence events.
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