Case Reports in Medicine (Jan 2012)

Thrombocytopenia in the Setting of Hemodialysis Using Biocompatible Membranes

  • Kathryn B. Muir,
  • Clifford D. Packer

DOI
https://doi.org/10.1155/2012/358024
Journal volume & issue
Vol. 2012

Abstract

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Thrombocytopenia is a known potential side effect of hemodialysis, however, it is rarely seen in patients who undergo hemodialysis using biocompatible membranes. This case demonstrates hemodialysis-associated thrombocytopenia with use of biocompatible dialysis membranes that expose blood directly to polysulfone. The thrombocytopenia resolved in this patient when the dialysis membrane was changed to a biocompatible model with a polyethylene glycol barrier layer preventing direct interaction between patient blood and polysulfone. The calculated Naranjo ADR score of 9 indicates a highly probable adverse reaction.