Emerging Infectious Diseases (Sep 2021)
Genomic Evolution of SARS-CoV-2 Virus in Immunocompromised Patient, Ireland
Abstract
We examined virus genomic evolution in an immunocompromised patient with prolonged severe acute respiratory syndrome coronavirus 2 infection. Genomic sequencing revealed genetic variation during infection: 3 intrahost mutations and possible superinfection with a second strain of the virus. Prolonged infection in immunocompromised patients may lead to emergence of new virus variants.
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