Sensors (Jan 2024)

Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy

  • Thi Ngoc Hang Bui,
  • Matthew Large,
  • Joel Poder,
  • Joseph Bucci,
  • Edoardo Bianco,
  • Raffaele Aaron Giampaolo,
  • Angelo Rivetti,
  • Manuel Da Rocha Rolo,
  • Zeljko Pastuovic,
  • Thomas Corradino,
  • Lucio Pancheri,
  • Marco Petasecca

DOI
https://doi.org/10.3390/s24020692
Journal volume & issue
Vol. 24, no. 2
p. 692

Abstract

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We assessed the accuracy of a prototype radiation detector with a built in CMOS amplifier for use in dosimetry for high dose rate brachytherapy. The detectors were fabricated on two substrates of epitaxial high resistivity silicon. The radiation detection performance of prototypes has been tested by ion beam induced charge (IBIC) microscopy using a 5.5 MeV alpha particle microbeam. We also carried out the HDR Ir-192 radiation source tracking at different depths and angular dose dependence in a water equivalent phantom. The detectors show sensitivities spanning from (5.8 ± 0.021) × 10−8 to (3.6 ± 0.14) × 10−8 nC Gy−1 mCi−1 mm−2. The depth variation of the dose is within 5% with that calculated by TG-43. Higher discrepancies are recorded for 2 mm and 7 mm depths due to the scattering of secondary particles and the perturbation of the radiation field induced in the ceramic/golden package. Dwell positions and dwell time are reconstructed within ±1 mm and 20 ms, respectively. The prototype detectors provide an unprecedented sensitivity thanks to its monolithic amplification stage. Future investigation of this technology will include the optimisation of the packaging technique.

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