Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation
A. Diez-Perez,
M.L. Bouxsein,
E.F. Eriksen,
S. Khosla,
J.S. Nyman,
S. Papapoulos,
S.Y. Tang
Affiliations
A. Diez-Perez
Department of Internal Medicine, Hospital del Mar-IMIM, Autonomous University of Barcelona and RETICEF, Instituto Carlos III, Spain; Corresponding author at: Department of Internal Medicine, Hospital del Mar, P. Maritim 25-29, 08003 Barcelona, Spain.
M.L. Bouxsein
Center for Advanced Orthopedic Studies, Beth Isreal Deaconess Medical Center and Department of Orthopedic Surgery, Harvard Medical School, Boston, MA, USA
E.F. Eriksen
Dept. of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, Oslo, Norway
S. Khosla
Division of Endocrinology and Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA
J.S. Nyman
Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA
S. Papapoulos
Center for Bone Quality, Leiden University Medical Center, Leiden, The Netherlands
S.Y. Tang
Department of Orthopaedic Surgery, Washington University in St Louis, St Louis, MO, USA
Impact microindentation is a novel method for measuring the resistance of cortical bone to indentation in patients. Clinical use of a handheld impact microindentation technique is expanding, highlighting the need to standardize the measurement technique. Here, we describe a detailed standard operation procedure to improve the consistency and comparability of the measurements across centers. Keywords: Bone microindentation, Impact microindentation, Bone tissue characteristics
