Respiratory function in type II diabetes mellitus

Abstract

Background: Type 2 diabetes mellitus (DM) and metabolic syndrome (MetS) are particularly common medical disorders and are leading causes of morbidity and mortality worldwide. Pulmonary function can be affected by DM. Aim of the work: The study aimed to evaluate respiratory function tests and respiratory muscle in patients with type 2 diabetes mellitus and correlated it with disease duration and control. Subjects and methods: 45 male cases with type-2 diabetes were included as a study group; another age-matched 45 cases were included as a control group. Clinical data, respiratory functions were measured and correlated with disease duration and HA1c (diabetes control). Results: Mean duration of diabetes mellitus was 7.62 ± 2.63 years, while mean HA1c was 7.48 ± 0.32.0. There was a significant decrease of TLC, FVC, FEV1, PEFR, PImax and PEmax in the study group, when compared to the control group. On the other hand, no significant difference was found between the two groups as regards FEV1/FVC. On the other hand, there was an inverse, significant correlation between HA1c and DM durations from one side and each of FVC, FEV1 and PImax from the other side. Conclusion: Patients with type-2 diabetes had a restrictive respiratory defect and glycemic levels and duration of disease are probably major determinants of lung pathology. However, these findings require further validation in subsequent research.

Keywords

• Pulmonary function
• Respiratory muscle
• Type 2 diabetes