Synthesis of metal nanoparticles using Heliconia rostrata leaf extract and their antiproliferative and apoptotic property

Abstract

The silver and gold nanoparticles were biosynthesized using leaves of a pharmacologically important plant Heliconia rostrata. A rapid, eco-friendly, cost-effective and one-step process of synthesis has been achieved, thus produced nanoparticles were characterized by UV–visible, FT-IR, XRD and TEM spectral studies. Further, newly synthesized nanoparticles were used to study the induction of apoptotic activity on EAT cells. These two types of nanoparticles showed antiproliferative and apoptotic property in mice model. The outcome of this study could be useful for the development of value added products from indigenous medicinal plants, which has biomedical applications.

Keywords

• Heliconia rostrate
• Nanoparticles
• Anti-proliferative activity