Nature Communications (Sep 2022)

Molecular basis for polysaccharide recognition and modulated ATP hydrolysis by the O antigen ABC transporter

  • Nicholas Spellmon,
  • Artur Muszyński,
  • Ireneusz Górniak,
  • Jiri Vlach,
  • David Hahn,
  • Parastoo Azadi,
  • Jochen Zimmer

DOI
https://doi.org/10.1038/s41467-022-32597-2
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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Gram negative microbes strategically equip lipopolysaccharides with O antigens to expand the extracellular envelope. Here, the authors examine how the O antigen is captured by a special class of ABC transporters containing a carbohydrate-binding module accessory.