Study on the regulation of degradation performance of polyethylene glycol nanofiber membranes by urushiol

Qian-Yu Yuan; Lan Yang; Ting-Ting Li; Bing-Chiuan Shiu; Ching-Wen Lou; Jia-Horng Lin

Polymer Testing (Nov 2023)

Study on the regulation of degradation performance of polyethylene glycol nanofiber membranes by urushiol

Qian-Yu Yuan,
Lan Yang,
Ting-Ting Li,
Bing-Chiuan Shiu,
Ching-Wen Lou,
Jia-Horng Lin

Affiliations

Qian-Yu Yuan: Innovation Platform of Intelligent and Energy-Saving Textiles, School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China
Lan Yang: Innovation Platform of Intelligent and Energy-Saving Textiles, School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China
Ting-Ting Li: Innovation Platform of Intelligent and Energy-Saving Textiles, School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China; Tianjin and Ministry of Education Key Laboratory for Advanced Textile Composite Materials, Tiangong University, Tianjin 300387, China
Bing-Chiuan Shiu: Fujian Key Laboratory of Novel Functional Textile Fibers and Materials, Minjiang University, Fuzhou 350108, China; College of Material and Chemical Engineering, Minjiang University, Fuzhou 350108, China; Corresponding author. College of Material and Chemical Engineering, Minjiang University, Fuzhou 350108, China.
Ching-Wen Lou: Innovation Platform of Intelligent and Energy-Saving Textiles, School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China; Fujian Key Laboratory of Novel Functional Textile Fibers and Materials, Minjiang University, Fuzhou 350108, China; Department of Bioinformatics and Medical Engineering, Asia University, Taichung City 413305, Taiwan; Department of Medical Research, China Medical University Hospital, China Medical University, Taichung City 404333, Taiwan; Corresponding author. Department of Bioinformatics and Medical Engineering, Asia University, Taichung City 413305, Taiwan.
Jia-Horng Lin: Advanced Medical Care and Protection Technology Research Center, Department of Fiber and Composite Materials, Feng Chia University, Taichung City 407102, Taiwan; School of Chinese Medicine, China Medical University, Taichung City 404333, Taiwan; Advanced Medical Care and Protection Technology Research Center, College of Textile and Clothing, Qingdao University, Qingdao 266071, China; Corresponding author. Advanced Medical Care and Protection Technology Research Center, Department of Fiber and Composite Materials, Feng Chia University, Taichung City 407102, Taiwan.

Journal volume & issue: Vol. 128
p. 108240

Abstract

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This study explores a new type of nanofiber membrane using water-soluble polymer material, polyethylene glycol (PEG), as the main raw material. The membrane is prepared by combining PEG with polyvinyl pyrrolidone (PVP) and urushiol (UR) through electrospinning. The research findings demonstrate that the degradation rate of the nanofiber membrane can be controlled by adjusting the UR content, enabling the production of wound dressings that match the required healing time. Additionally, the addition of UR provides the nanofiber membrane with certain antimicrobial effects against Escherichia coli and Staphylococcus aureus. When combined with nano zinc oxide (ZnO), the antimicrobial effect of the nanofiber membrane reaches 99%. Furthermore, cytotoxicity experiments conducted on the nanofiber membrane meet the relevant standards. The results of this study provide a reliable option for researching and developing PEG materials with improved drug delivery effects. The nanofiber membrane possesses the characteristic of regulating degradation rate and shows potential for application in the field of wound healing, providing support for wound repair and tissue remodeling.

Published in Polymer Testing

ISSN: 0142-9418 (Print); 1873-2348 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Technology: Chemical technology: Polymers and polymer manufacture
Website: https://www.journals.elsevier.com/polymer-testing

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