Research progress on the role of secretory protein Metrnl in different diseases

Abstract

Metrnl is a new cytokine with homologous orignination from neurotrophic factor Meteorin. Meanwhile, as a secreting protein, its gene and products show low tissue specificity and is widely expressed in different tissues of host. Similar to neurotrophic factor, adipocytokines, inflammatory factor and muscle factor, the protein plays a role in neural development, immune inflammatory response and metabolism and so on.

Keywords

• meteorin-like protein(metrnl)|neurotrophic factor|energy metabolism|insulin resistance|immunoregulation