OncoTargets and Therapy (Dec 2020)

Success of 125I-Seed Treatment in Vulvar Squamous-Cell Carcinoma with Aplastic Anemia: A Case Report

  • Ni Q,
  • Pan C,
  • Guo Q,
  • Wang P,
  • Sun G,
  • Xiao S,
  • Dai S

Journal volume & issue
Vol. Volume 13
pp. 12561 – 12566

Abstract

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Qingtao Ni,1 Chi Pan,2 Qing Guo,1 Peng Wang,1 Guangzhi Sun,1 Shujun Xiao,3 Shengbin Dai1 1Department of Oncology, Jiangsu Taizhou People’s Hospital, Taizhou 225300, People’s Republic of China; 2Department of General Surgery, Jiangsu Taizhou People’s Hospital, Taizhou 225300, People’s Republic of China; 3Department of General Practice, Jiangsu Taizhou People’s Hospital, Taizhou 225300, People’s Republic of ChinaCorrespondence: Shujun XiaoDepartment of General Practice, Jiangsu Taizhou People’s Hospital, Taizhou 225300, People’s Republic of ChinaTel +86 139-5261-9404Email [email protected] DaiDepartment of Oncology, Jiangsu Taizhou People’s Hospital, Taizhou 225300, People’s Republic of ChinaTel +86 135-1515-5717Email [email protected]: Vulvar squamous-cell carcinoma (SCC) is a rare disease that occurs mainly in postmenopausal women. Chemo/radiotherapy with or without surgery is the most important modality for treatment of advanced vulvar cancer. A case of vulvar SCC with aplastic anemia was treated using 125I seeds in our department, because surgery and chemotherapy were not possible due to low platelets, leaving radiotherapy as the lone therapeutic option. 125I seeds present an alternative option for treatment of patients with vulvar SCC and local relapse with lymph-node metastasis following previous radiotherapy.Keywords: vulvar squamous-cell carcinoma, I-125 seeds, aplastic anemia, 125I

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