HTA und aktuelle Herausforderungen: Harmonisierung, Real World Data und Surrogatparameter

Abstract

Health Technology Assessment is one of the standard instruments in support of the decision-making to define the public health services both internationally and in the German health care system. Besides systematic reviews, benefit-harm-analyses, health economic evaluations, and, decision-analytic modelling, especially epidemiological and biometrical questions and methods play a key role. From this perspective discussions on increased European cooperation including calls for wider harmonization are attracting greater interests.The overall aim is, to present at the GMDS workshop relevant information on this emerging field of harmonization in Europe across similarities and differences in the HTA process. Current developments around the composition of the EU-HTA Network are provided. This network accepts the challenge to define and establish a “Joint Work” across Europe. Special emphasis was placed on the discussion on “Harmonization of HTA: is it a threat or does it mean support?”. Furthermore, methodological discussions and questions are being addressed: “Are Real World Data and Surrogates possible parameters for decision-making or HTA?”

Keywords

• HTA
• systematic reviews
• real world data
• policy
• technology assessment
• surrogate endpoints
• biological markers
• endpoint determination
• thresholds
• validation techniques
• correlation of data
• estimation techniques
• biometry
• simulation
• theoretical study
• medicine, evidence-based
• decision support techniques