Effectiveness of Blood Urea Nitrogen to Albumin Ratio and C-reactive Protein to Albumin Ratio in Prediction of Medical Treatment Failure for Tuboovarian Abscess

Abstract

Objective: This study aimed to compare the clinical characteristics of patients with tuboovarian abscess who responded to medical treatment (MT) and those who underwent surgical intervention (SI) because of MT failure. Methods: Patients who were cured by MT were defined as Group 1 (n=25, 55.6%) and patients requiring SI were defined as Group 2 (n=20, 44.4%). The largest diameter of the abscess (cm) detected by ultrasound was recorded. Blood urea nitrogen to albumin (A) ratio (BAR) and C-reactive protein (CRP) to albumin (A) ratio (CAR) calculated according to laboratory tests on the first day of hospitalization. Results: BAR and CAR were analyzed higher in Group 2 (p=0.3; p=0.5, respectively). The abscess size of Group 2 was statistically significantly higher than that of Group 1 (p=0.002). Abscess size greater than 5.8 cm was calculated as the cut-off point indicating failure of MT (p=0.003). The cut-off points of BAR 2.7 (p=0.3) and CAR 35.6 (p=0.09) were indicators of SI. According to the univariate and multivariate analyses, abscess size was an independent factor for predicting SI (p=0.01; p=0.03, respectively). Conclusion: Our study suggested that BAR and CAR may be used to predict candidates for SI. Future prospective controlled studies are required to confirm our findings.

Keywords

• blood urea nitrogen to albumin ratio
• c-reactive protein to albumin ratio
• surgical intervention
• tuboovarian abscess