Cancers (May 2021)

Reply to Krupenko et al. Comment on “Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer <em>Cancers</em> 2020, <em>12</em>, 1382”

  • Seon-Hyeong Lee,
  • Yoon Jeon,
  • Joon-Hee Kang,
  • Hyonchol Jang,
  • Kyeong-Man Hong,
  • Dongwan Hong,
  • Ho Lee,
  • Soo-Youl Kim

DOI
https://doi.org/10.3390/cancers13092238
Journal volume & issue
Vol. 13, no. 9
p. 2238

Abstract

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In the Cancers paper, we observed the increase ALDH1L1 protein expression following oncogenesis, as well as a therapeutic effect, by deleting the Aldh1l1 gene in KrasLA2 mice, a model of spontaneous non-small cell lung cancer (NSCLC) [...]

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