HYPOLIPIDAEMIC EFFECT OF Allium sativum IN RABBITS

Abstract

The hypolipidaemic effect of Allium sativum was studied in rabbits and was compared with Gemfibrozil (120 mg/kg) orally which served as positive control drug. Aqueous extract of A .sativum is effective as a hypolipidaemic agent and this finding is further asserted by the simultaneous histopathological studies carried out. The indigenous agent was capable of correcting the fatty changes produced by the fat containing diet to a considerable extent. The efficacy in lowering plasma cholesterol and triglyceride was comparable to that of Gemfibrozil, as shown by the statistical analysis of the results obtained