Control of lecithin biosynthesis in erythrocyte membranes

Abstract

The detailed relationship between the relative composition of the potential precursor acids, the esterification rates of their CoA thiol ester derivatives, and the relative composition of the fatty acids in the product, lecithin, which was isolated from normal erythrocytes, suggests that in humans the stromal acyltransferases could be the significant enzymatic factor controlling the fatty acid composition at the 2-position of lecithin in erythrocytes.

Keywords

• erythrocyte
• acyl-CoA: monoacylglycerophosphoryl choline acyltransferase
• lecithin
• lysolecithin
• fatty acid composition
• plasma free fatty acids