Jichu yixue yu linchuang (Feb 2020)

Effect of gender, age and season on serum 25-hydroxyvitamin D level

  • WANG Dan-chen, YIN Yi-cong, YU Song-lin, ZHANG Rui-li, GAO Xue-hui, LI Hong-lei, CHENG Xin-qi, QIU Ling

Journal volume & issue
Vol. 40, no. 2
pp. 151 – 154

Abstract

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Objective To explore the effect of gender, age and season on serum 25-hydroxyvitamin D(25OHD). Methods Clinical data was collected from the laboratory information system at the Peking Union Medical College Hospital from December 2014 to October 2018. A total of 34 062 25OHD samples were obtained and analyzed. 25OHD concentrations were measured using a Roche e601 automatic analyzer. Regression analysis was used to explore the effect of gender, age and season on 25OHD level. Results The median serum 25OHD concentration was significantly higher in males than that in females(P＜0.001). The median serum 25OHD concentration at the peak level in August was 22.1 ng/mL. Regression analysis revealed that summer had the highest impact on 25OHD (standardization coefficient=0.273). Conclusions Gender and season significantly affected serum 25OHD levels.

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