THE CONDITION OF SYSTEMIC IMMUNITY IN PATIENTS WITH ALLERGIC ASTHMA LIVING IN R EPUBLIK OF H KAKASIA

Abstract

Abstract. The subpopulation structure of immunocompetent cells of peripheral blood, concentration of IgA, IgM, IgG, IgE and serum levels of IL-4 and IL-10 for the patients was studied. Reduced contents of CD8+, CD56+ lymphocytes and increased contents of CD4+, CD22+ lymphocytes, serum levels of IgA, IgM, IgG, IgE are revealed in Hkakass with asthma compared to healthy Hkakass. It was also revealed in Hkakass with asthma that contents of CD3+ and CD8+ lymphocytes, serum concentration of IgA, IgE increased compared to Caucasoids with asthma. The serum level of cytokines IL-4 were found to be considerably increased in Hkakass with asthma compared to healthy Hkakass and to Caucasoids with asthma. On the other hand, the comparison of concentration of IL-10 showed that serum level was higher in Caucasoids with asthma than Hkakass with asthma.

Keywords

• allergic asthma
• il-4
• il-10
• immunocompetent cells subpopulations
• serum immunoglobulins