Functional Effect of Lesser Yam Symbiotic Yoghurt on Hypercholesterolemia Wistar Rats

Abstract

Synbiotic lesser yam yoghurt is fermented drink made from the mixture of cow’s milk and lesser yam extract which has functional benefits. Lesser yam yoghurt contains lactic acid bacteria, lactic acid, inulin, and soluble fiber which can improve the lipid profile of hypercholesterolemia sufferers. This study aims to determine the effect of the intake of lesser yam yoghurt on the lipid profile of hypercholesterolemia wistar rats. This study used nested randomized design with two factors, the first factor was a feeding group (0,1,2,3,4 ml/day, while the second factor was the time of blood collection (0, week 1 and week 2). The data obtained were analyzed by using ANAVA and further test DMRT (Duncan Multiple Range Test) with a level of 5%. The results showed that giving lesser yam yoghurt for 2 weeks had a significant effect on the lipid profile improvement. Rats from 4 ml of yoghurt treatment experienced a decrease in total serum cholesterol by 48.4%, triglyceride levels by 35.8% and LDL levels by 65,5% and an increase in serum HDL levels by 150.3%. So it can be concluded that the intake of synbiotik lesser yam yoghurt has functional benefits in improving the lipid profile of hypercholesterolemia rats.

Keywords

• hypercholesterolemia rats
• synbiotic yoghurt
• lesser yam tubers
• lipid profile