Nature Communications (Jul 2022)

Topological digestion drives time-varying rheology of entangled DNA fluids

  • D. Michieletto,
  • P. Neill,
  • S. Weir,
  • D. Evans,
  • N. Crist,
  • V. A. Martinez,
  • R. M. Robertson-Anderson

DOI
https://doi.org/10.1038/s41467-022-31828-w
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 13

Abstract

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Understanding and controlling the rheology of polymeric complex fluids is of fundamental importance in both industry and biology. Here, Michieletto et al. show how to achieve time-dependent rheology of DNA solutions via enzymatically-driven architectural alterations by restriction endonucleases.