Разработка и регистрация лекарственных средств (May 2023)
Pharmacotherapy of Oncological Diseases: Search for New Drugs and Approaches
Abstract
Introduction. This publication represents the materials of the traditional scientific conference of senior students of the Institute of Pharmacy of the Sechenov University and the Faculty of Fundamental Medicine of the Lomonosov Moscow State University under the general motto "Drug. Medicine or... Difficulties in translation", which took place on May 27, 2022. Every year the topic of such a conference is the most pressing medical and social problems related to the effectiveness and safety of medicines. This conference was timed to coincide with the 10th anniversary international congress on diseases of the head and neck organs, which was taking place at that time, and was devoted to the problem of pharmacotherapy of oncological diseases.In Russia, as well as in the world, oncological diseases are widespread and occupy the second place among the causes of death. So, according to statistics, every 40th person in Russia has an oncological disease.Thousands of researchers around the world are striving to understand the etiology of cancer, improve the efficiency of diagnosis and treatment of the disease, ensuring slow but steady progress in solving these problems.Early diagnosis and timely targeted treatment are the key to successful therapy and a favorable outcome.The presentations discussed the main directions in the development of anticancer drugs that provide greater efficacy and safety of treatment, modern approaches to early cancer diagnosis using microRNA as tumor markers. Of great interest was the report on the possibility of predicting the toxicity of drugs even before the stage of chemical synthesis on the basis of computer-aided drug design. Also, attention was paid to the problems of palliative care and rehabilitation of cancer patients, psychological, ethical and legal aspects of this. Discussion and medical assessment of these issues will certainly arouse the interest of a fairly wide audience. The following are only three reports from those that have sounded, giving an idea of the "classical" methods, a new direction in treatment, and the technological implementation of targeted tumor therapy.
